Research Techniques Made Simple: SYSTEMATIC REVIEWS AND META-ANALYSIS Q&A

Below are Questions and Answers relating to the Research Techniques Made Simple article “The Role of Systematic Reviews and Meta-Analysis in Dermatology” (J Invest Derm 132:e2, 2012; doi:10.1038/jid.2012.392)

 

QUESTIONS:

                             

  1. GRADE and SORT describe which of the following?
    1. Techniques for assessing the risk of bias in individual studies
    2. Guidelines on how to report systematic reviews and meta-analyses
    3. Types of fixed-effect models used in statistical meta-anlaysis
    4. Methods for rating the strength of clinical recommendations

 

  1. Which of the following is true regarding random-effects models?
    1. They are generally consider more appropriate if the I2 value is > 40%
    2. They are rarely used in meta-analysis
    3. They are often employed to assess the risk of bias in individual studies
    4. They are most appropriate when between-study heterogeneity is low

 

 

 

ANSWERS:

 

1. d: Methods for rating the strength of clinical recommendations

 

2. a: They are generally consider more appropriate if the I2 value is > 40%

 

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